Anna E Grzegorzewicz Selected Research

Tuberculosis (Tuberculoses)

2/2015	Covalent modification of the Mycobacterium tuberculosis FAS-II dehydratase by Isoxyl and Thiacetazone.
11/2014	Novel insights into the mechanism of inhibition of MmpL3, a target of multiple pharmacophores in Mycobacterium tuberculosis.
1/2013	Subfractionation and analysis of the cell envelope (lipo)polysaccharides of Mycobacterium tuberculosis.
11/2012	A common mechanism of inhibition of the Mycobacterium tuberculosis mycolic acid biosynthetic pathway by isoxyl and thiacetazone.
5/2012	Screening a library of 1600 adamantyl ureas for anti-Mycobacterium tuberculosis activity in vitro and for better physical chemical properties for bioavailability.
2/2012	Inhibition of mycolic acid transport across the Mycobacterium tuberculosis plasma membrane.
12/2008	Development of a microtitre plate-based assay for lipid-linked glycosyltransferase products using the mycobacterial cell wall rhamnosyltransferase WbbL.

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Anna E Grzegorzewicz Research Topics

Disease

7	Tuberculosis (Tuberculoses) 02/2015 - 12/2008
3	Infections 12/2021 - 01/2013
2	Dehydration (Water Stress) 01/2020 - 02/2015
1	Skin Ulcer 12/2021
1	Multidrug-Resistant Tuberculosis (Drug-Resistant Tuberculosis) 01/2013

Drug/Important Bio-Agent (IBA)

3	Type II Fatty Acid SynthaseIBA 01/2020 - 11/2012
2	Hydro-Lyases (Dehydratases)IBA 01/2020 - 11/2012
2	EnzymesIBA 01/2020 - 02/2015
2	thiocarlideIBA 02/2015 - 11/2012
2	Thioacetazone (Thiacetazone)IBA 02/2015 - 11/2012
2	ProdrugsIBA 02/2015 - 11/2012
2	Mycolic Acids (Mycolic Acid)IBA 11/2012 - 02/2012
1	mycolactoneIBA 12/2021
1	RNA (Ribonucleic Acid)IBA 12/2021
1	Virulence Factors (Pathogenicity Factors)IBA 12/2021
1	Protons (Proton)IBA 11/2014
1	Pharmaceutical PreparationsIBA 11/2014
1	CarbohydratesIBA 01/2013
1	Antitubercular AgentsIBA 01/2013
1	Polysaccharides (Glycans)IBA 01/2013
1	Fatty Acids (Saturated Fatty Acids)IBA 11/2012
1	Urea (Carbamide)FDA LinkGeneric 05/2012
1	Epoxide HydrolasesIBA 05/2012
1	Membrane Transport Proteins (Biological Pump)IBA 02/2012
1	GlycolipidsIBA 02/2012
1	TrehaloseIBA 02/2012
1	arabinogalactanIBA 02/2012

Therapy/Procedure

1	Oral Administration 05/2012
1	Therapeutics 12/2008